NMR is still the premier analytical tool for compound identity, quantitation, food authenticity, reaction understanding – and so many more! The list of uses is growing daily, especially as more affordable instrumentation becomes commonplace.
Our 30+ years of experience can help you with any requirements, such as:
NMR in pharmaceutical R&D
NMR plays a pivotal role in many aspects of pharmaceutical research, development, and API production. Once the reserve of small-molecule pharmaceuticals, NMR has found a new role with mAb quality assurance through Higher Order Structure (HOS) verification.
With a deep understanding of pharma, we are ideally suited to help you use NMR to its full potential.
MestReNova is the premier software for spectral processing and analysis. Use our considerable expertise with the product to help you understand and use the software correctly, and to its full potential. Let us devise a course that is customised to your needs.
qNMR – and AUTOMATION
The use of NMR for quantitation and mixtures analysis is growing rapidly! We have in-depth, specialised knowledge for the topic, and can advise on almost any application. We are specially involved in many aspects of compound purity determination, foods and nutraceuticals analysis and authentication.
Our special involvement extends to outreach programs like ValidNMR, and ISO standards bodies.
The qNMR and targeted mixtures analysis components of Mnova were our special projects. New work is in the full automation of the process, with regard for GxP requirements.
IND DOCUMENT EXPERIMENTAL DATA
ROUTE OPTIMISATION THROUGH REACTION UNDERSTANDING
API QUALITY ASSURANCE AND PURITY TESTING
Come to us for training in basic NMR, or specialist topics:
NMR TO DETERMINE mAb DRUG HIGHER ORDER STRUCTURE (HOS)
USING MESTRELAB MNOVA
NMR is increasing used to characterise formulated drug substances. For example, qNMR can be used to determine the amount of active pharmaceutical ingredient (API) in the tablets, or the concentration of several APIs in a complex formulation. NMR is an excellent method for structure determinationand salt form.
Patent infringement litigagtion can rely on these NMR-based analyses, and expert opinion is required to critique procedures in Product Descriptions. We have experience working with top patent attorneys to generate appropriate documents required for the preparation of a legal procedure. We can also appear in court for cross examination.
CONSIDER THIS OPTION IF: